contact@lextrobio.com

Antibody Discovery

We adopt a multi-pronged approach to generate patentable therapeutic, as well as diagnostic antibodies that are mono- or multi-specific towards their antigens. The application of next-generation technologies and tools in the generation, validation, and production of antibodies helps to significantly shorten timelines to reach clinics in 18 – 24 months.

Our capabilities include the generation of hybridoma by immunizations, phage display libraries, and isolation of antigen-specific single B cells to clone and express single chain fragment variables (scFv) for the production of naturally or randomly paired antibodies. Our expertise is in the generation of antagonistic or agonistic mono- or multi-specific therapeutic antibodies in areas such as immune-oncology, auto-immune and infectious diseases. We generate humanized or fully human therapeutic antibodies by applying various engineering tools such as CDR, and SDR grafting.

Therapeutic Antibody Services

FULLY
HUMAN MABS
(NATURALLY
OR RANDOMLY
PAIRED)

PHAGE
DISPLAY

CELL-
PENETRATING
ANTIBODIES

AFFINITY
MATURATION

 MULTI-
SPECIFIC
ANTIBODIES

DIAGNOSTIC AND REAGENT ANTIBODY SERVICES

MONO &
POLYCLONAL
ANTIBODIES

LFA / ELISA
KITS FOR
DIAGNOSTIC
APPLICATIONS

Scroll to Top