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In-vitro Services

At Lextro Bio Solutions, we provide target-specific binding as well as functional assays, wherein the experimental data being produced meets the attributes of quality and reproducibility. Screening assays include ligand-receptor binding, competitive binding, affinity determination, etc. Our in-vitro cell-based screening assays encompass two-dimensional (2D) as well as three-dimensional (3D) assays to determine potency, functionality, receptor occupancy, physiological responses, cell migrations & invasions, etc. In addition to standard assays, we offer specialized or customized in-vitro assays wherein the effects of mono, as well as drug combinations, are studied in standard cell lines or primary cells.

Screening & Lead Identification for Novel Biological, Chemical or Nucleic Acid Entities:
2D & 3D cell cultures (Spheroids & organoids, PDO) for potency determination
Migration &
invasion assays
Hypoxia, ROS,
ATP etc.
Flow cytometric
analysis of TILs
& PBMC
T&B cells, NK cells,
DC & Myeloid cells
Phosphorylation assays adopting flowcytometry, western blot, ELISA etc.
ELISPOT
assays
ADCC / CDC
assays
Functional assays (Agonist & Antagonist activities)
Receptor Occupancy assays
Binding & Affinity assays
Bioassays for
biosimilars
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